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Prion protein NMR structure and familial human spongiform encephalopathies

The refined NMR structure of the mouse prion protein domain mPrP(121–231) and the recently reported NMR structure of the complete 208-residue polypeptide chain of mPrP are used to investigate the structural basis of inherited human transmissible spongiform encephalopathies. In the cellular form of m...

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Auteurs principaux: Riek, Roland, Wider, Gerhard, Billeter, Martin, Hornemann, Simone, Glockshuber, Rudi, Wüthrich, Kurt
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC21698/
https://ncbi.nlm.nih.gov/pubmed/9751723
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