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Promoter opening via a DNA fork junction binding activity

The rate-limiting step in transcriptional initiation typically is opening the promoter DNA to expose the template strand. Opening is tightly regulated, but how it occurs is not known. These experiments identify an activity, recognition of specific DNA fork junctions, and suggest that it is critical...

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Autors principals: Guo, Yuli, Gralla, Jay D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC21696/
https://ncbi.nlm.nih.gov/pubmed/9751721
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