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Promoter opening via a DNA fork junction binding activity

The rate-limiting step in transcriptional initiation typically is opening the promoter DNA to expose the template strand. Opening is tightly regulated, but how it occurs is not known. These experiments identify an activity, recognition of specific DNA fork junctions, and suggest that it is critical...

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Bibliografske podrobnosti
Main Authors: Guo, Yuli, Gralla, Jay D.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC21696/
https://ncbi.nlm.nih.gov/pubmed/9751721
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