Biochemical characterization of a Neisseria meningitidis polysialyltransferase reveals novel functional motifs in bacterial sialyltransferases

The extracellular polysaccharide capsule is an essential virulence factor of Neisseria meningitidis, a leading cause of severe bacterial meningitis and sepsis. Serogroup B strains, the primary disease causing isolates in Europe and America, are encapsulated in α-2,8 polysialic acid (polySia). The ca...

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Main Authors: Freiberger, Friedrich, Claus, Heike, Günzel, Almut, Oltmann-Norden, Imke, Vionnet, Justine, Mühlenhoff, Martina, Vogel, Ulrich, Vann, Willie F, Gerardy-Schahn, Rita, Stummeyer, Katharina
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2007
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169525/
https://ncbi.nlm.nih.gov/pubmed/17662040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2007.05862.x
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