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Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo

The loss of chromosomal integrity from DNA double-strand breaks introduced into mammalian cells by ionizing radiation results in the specific phosphorylation of histone H2AX on serine residue 139, yielding a specific modified form named γ-H2AX. An antibody prepared to the unique region of human γ-H2...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rogakou, Emmy P., Boon, Chye, Redon, Christophe, Bonner, William M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169482/
https://ncbi.nlm.nih.gov/pubmed/10477747
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