A Nuclear Action of the Eukaryotic Cochaperone Rap46 in Downregulation of Glucocorticoid Receptor Activity

RAP46 is a eukaryotic cochaperone that associates with several proteins, including the heat shock protein hsp70/hsc70 and the glucocorticoid receptor (GR). Here we show a downregulation of GR-mediated transactivation by RAP46 via a mechanism independent of a cytoplasmic action of this cochaperone. W...

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Detaylı Bibliyografya
Asıl Yazarlar: Schneikert, Jean, Hübner, Susanne, Martin, Elke, Cato, Andrew C.B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 1999
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Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169481/
https://ncbi.nlm.nih.gov/pubmed/10477749
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