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UBE2T, the Fanconi Anemia Core Complex, and FANCD2 Are Recruited Independently to Chromatin: a Basis for the Regulation of FANCD2 Monoubiquitination

The Fanconi anemia (FA) nuclear core complex and the E2 ubiquitin-conjugating enzyme UBE2T are required for the S phase and DNA damage-restricted monoubiquitination of FANCD2. This constitutes a key step in the FA tumor suppressor pathway, and much attention has been focused on the regulation at thi...

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Sonraí Bibleagrafaíochta
Main Authors: Alpi, Arno, Langevin, Frederic, Mosedale, Georgina, Machida, Yuichi J., Dutta, Anindya, Patel, Ketan J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169426/
https://ncbi.nlm.nih.gov/pubmed/17938197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00504-07
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