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Sumoylation Modulates the Assembly and Activity of the Pre-mRNA 3′ Processing Complex

Eukaryotic pre-mRNA 3′-end formation is catalyzed by a complex set of factors that must be intricately regulated. In this study, we have discovered a novel role for the small ubiquitin-like modifier SUMO in the regulation of mammalian 3′-end processing. We identified symplekin, a factor involved in...

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Autors principals: Vethantham, Vasupradha, Rao, Nishta, Manley, James L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169417/
https://ncbi.nlm.nih.gov/pubmed/17923699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01186-07
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