T-bet's Ability To Regulate Individual Target Genes Requires the Conserved T-Box Domain To Recruit Histone Methyltransferase Activity and a Separate Family Member-Specific Transactivation Domain

Appropriate cellular differentiation and specification rely upon the ability of key developmental transcription factors to precisely establish gene expression patterns. These transcription factors often regulate epigenetic events. However, it has been unclear whether this is the only role that they...

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Main Authors: Lewis, Megan D., Miller, Sara A., Miazgowicz, Michael M., Beima, Kristin M., Weinmann, Amy S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2007
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169399/
https://ncbi.nlm.nih.gov/pubmed/17923685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01615-07
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