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Gelsolin Deficiency Blocks Podosome Assembly and Produces Increased Bone Mass and Strength

Osteoclasts are unique cells that utilize podosomes instead of focal adhesions for matrix attachment and cytoskeletal remodeling during motility. We have shown that osteopontin (OP) binding to the α(v)β(3) integrin of osteoclast podosomes stimulated cytoskeletal reorganization and bone resorption by...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Chellaiah, Meenakshi, Kizer, Neil, Silva, Matthew, Alvarez, Ulises, Kwiatkowski, David, Hruska, Keith A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2000
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169374/
https://ncbi.nlm.nih.gov/pubmed/10684249
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