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Dilation and degradation of the brain extracellular matrix enhances penetration of infused polymer nanoparticles
This study investigates methods of manipulating the brain extracellular matrix (ECM) to enhance the penetration of nanoparticle drug carriers in convection-enhanced delivery (CED). A probe was fabricated with two independent microfluidic channels to infuse, either simultaneously or sequentially, nan...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2169304/ https://ncbi.nlm.nih.gov/pubmed/17920047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2007.08.050 |
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