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Regulation of the Il4 Gene Is Independently Controlled by Proximal and Distal 3′ Enhancers in Mast Cells and Basophils

Mast cells and basophils are known to be a critical interleukin 4 (IL-4) source for establishing Th2 protective responses to parasitic infections. Chromatin structure and histone modification patterns in the Il13/Il4 locus of mast cells were similar to those of IL-4-producing type 2 helper T cells....

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Hlavní autoři: Yagi, Ryouji, Tanaka, Shinya, Motomura, Yasutaka, Kubo, Masato
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169195/
https://ncbi.nlm.nih.gov/pubmed/17908791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00631-07
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