Vitamin K Induces Osteoblast Differentiation through Pregnane X Receptor-Mediated Transcriptional Control of the Msx2 Gene

Vitamin K is a fat-soluble vitamin that serves as a coenzyme for vitamin K-dependent carboxylase. Besides its canonical action, vitamin K binds to the steroid and xenobiotic receptor (SXR)/pregnane X receptor (PXR) and modulates gene transcription. To determine if the osteoprotective action of vitam...

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Bibliographic Details
Main Authors: Igarashi, Mamoru, Yogiashi, Yoshiko, Mihara, Masatomo, Takada, Ichiro, Kitagawa, Hirochika, Kato, Shigeaki
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2007
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169156/
https://ncbi.nlm.nih.gov/pubmed/17875939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00813-07
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