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Structural Changes in Mcm5 Protein Bypass Cdc7-Dbf4 Function and Reduce Replication Origin Efficiency in Saccharomyces cerevisiae

Eukaryotic chromosomal replication is a complicated process with many origins firing at different efficiencies and times during S phase. Prereplication complexes are assembled on all origins in G(1) phase, and yet only a subset of complexes is activated during S phase by DDK (for Dbf4-dependent kina...

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מידע ביבליוגרפי
Main Authors: Hoang, Margaret L., Leon, Ronald P., Pessoa-Brandao, Luis, Hunt, Sonia, Raghuraman, M. K., Fangman, Walton L., Brewer, Bonita J., Sclafani, Robert A.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169039/
https://ncbi.nlm.nih.gov/pubmed/17724082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00997-07
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