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CDC7/DBF4 functions in the translesion synthesis branch of the RAD6 epistasis group in Saccharomyces cerevisiae.

CDC7 and DBF4 encode the essential Cdc7-Dbf4 protein kinase required for DNA replication in eukaryotes from yeast to human. Cdc7-Dbf4 is also required for DNA damage-induced mutagenesis, one of several postreplicational DNA damage tolerance mechanisms mediated by the RAD6 epistasis group. Several ge...

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Detalhes bibliográficos
Main Authors: Pessoa-Brandão, Luis, Sclafani, Robert A
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1471023/
https://ncbi.nlm.nih.gov/pubmed/15342501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.103.021675
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