Highly Pathogenic Avian Influenza H5N1 Viruses Elicit an Attenuated Type I Interferon Response in Polarized Human Bronchial Epithelial Cells

The unparalleled spread of highly pathogenic avian influenza A (HPAI) H5N1 viruses has resulted in devastating outbreaks in domestic poultry and sporadic human infections with a high fatality rate. To better understand the mechanism(s) of H5N1 virus pathogenesis and host responses in humans, we util...

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Detalhes bibliográficos
Main Authors: Zeng, Hui, Goldsmith, Cynthia, Thawatsupha, Pranee, Chittaganpitch, Malinee, Waicharoen, Sunthareeya, Zaki, Sherif, Tumpey, Terrence M., Katz, Jacqueline M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169033/
https://ncbi.nlm.nih.gov/pubmed/17855549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01134-07
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