A Recombinant Sendai Virus Is Controlled by CD4(+) Effector T Cells Responding to a Secreted Human Immunodeficiency Virus Type 1 Envelope Glycoprotein

The importance of antigen-specific CD4(+) helper T cells in virus infections is well recognized, but their possible role as direct mediators of virus clearance is less well characterized. Here we describe a recombinant Sendai virus strategy for probing the effector role(s) of CD4(+) T cells. Mice we...

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Autors principals: Brown, Scott A., Hurwitz, Julia L., Zirkel, Amy, Surman, Sherri, Takimoto, Toru, Alymova, Irina, Coleclough, Chris, Portner, Allen, Doherty, Peter C., Slobod, Karen S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2007
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168998/
https://ncbi.nlm.nih.gov/pubmed/17652379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00197-07
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