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Localization and Membrane Topology of Coronavirus Nonstructural Protein 4: Involvement of the Early Secretory Pathway in Replication

The coronavirus nonstructural proteins (nsp's) derived from the replicase polyproteins collectively constitute the viral replication complexes, which are anchored to double-membrane vesicles. Little is known about the biogenesis of these complexes, the membrane anchoring of which is probably me...

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Bibliographic Details
Main Authors: Oostra, M., te Lintelo, E. G., Deijs, M., Verheije, M. H., Rottier, P. J. M., de Haan, C. A. M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168994/
https://ncbi.nlm.nih.gov/pubmed/17855519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01506-07
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