Influenza Virus-Induced Type I Interferon Leads to Polyclonal B-Cell Activation but Does Not Break Down B-Cell Tolerance

The link between infection and autoimmunity is not yet well understood. This study was designed to evaluate if an acute viral infection known to induce type I interferon production, like influenza, can by itself be responsible for the breakdown of immune tolerance and for autoimmunity. We first test...

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Bibliographic Details
Main Authors: Woods, Anne, Monneaux, Fanny, Soulas-Sprauel, Pauline, Muller, Sylviane, Martin, Thierry, Korganow, Anne-Sophie, Pasquali, Jean-Louis
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2007
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168975/
https://ncbi.nlm.nih.gov/pubmed/17855528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00839-07
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