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The Human T-Cell Leukemia Virus Type 1 Tax Oncoprotein Requires the Ubiquitin-Conjugating Enzyme Ubc13 for NF-κB Activation

Ubiquitination of the human T-cell leukemia virus 1 Tax oncoprotein provides an important regulatory mechanism that promotes the Tax-mediated activation of NF-κB. However, the type of polyubiquitin chain linkages and the host factors that are required for Tax ubiquitination have not been identified....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shembade, Noula, Harhaj, Nicole S., Yamamoto, Masahiro, Akira, Shizuo, Harhaj, Edward W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168884/
https://ncbi.nlm.nih.gov/pubmed/17942533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01790-07
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