Increased Immunogenicity of a DNA-Launched Venezuelan Equine Encephalitis Virus-Based Replicon DNA Vaccine

A novel genetic vaccine that is based on a Venezuelan equine encephalitis virus (VEE) replicon launched from plasmid DNA is described. The plasmid encodes a VEE replicon under the transcriptional control of the cytomegalovirus immediate-early promoter (VEE DNA). The VEE DNA consistently expressed 3-...

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Bibliographic Details
Main Authors: Ljungberg, Karl, Whitmore, Alan C., Fluet, Meagan E., Moran, Timothy P., Shabman, Reed S., Collier, Martha L., Kraus, Annette A., Thompson, Joseph M., Montefiori, David C., Beard, Clayton, Johnston, Robert E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2007
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168848/
https://ncbi.nlm.nih.gov/pubmed/17913817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01799-07
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