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Ebola Virus VP24 Proteins Inhibit the Interaction of NPI-1 Subfamily Karyopherin α Proteins with Activated STAT1

The Zaire ebolavirus protein VP24 was previously demonstrated to inhibit alpha/beta interferon (IFN-α/β)- and IFN-γ-induced nuclear accumulation of tyrosine-phosphorylated STAT1 (PY-STAT1) and to inhibit IFN-α/β- and IFN-γ-induced gene expression. These properties correlated with the ability of VP24...

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Detalhes bibliográficos
Main Authors: Reid, St. Patrick, Valmas, Charalampos, Martinez, Osvaldo, Sanchez, Freddy Mauricio, Basler, Christopher F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168840/
https://ncbi.nlm.nih.gov/pubmed/17928350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01097-07
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