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RNA Editing of the Human Herpesvirus 8 Kaposin Transcript Eliminates Its Transforming Activity and Is Induced during Lytic Replication

Human herpesvirus 8 is the etiologic agent associated with Kaposi's sarcoma and primary effusion lymphoma (PEL). The K12 RNA, which produces as many as three variants of the kaposin protein, as well as a microRNA, is the most abundant transcript expressed in latent Kaposi's sarcoma-associa...

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Detalhes bibliográficos
Main Authors: Gandy, Sharon Z., Linnstaedt, Sarah D., Muralidhar, Sumitra, Cashman, Kathleen A., Rosenthal, Leonard J., Casey, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168827/
https://ncbi.nlm.nih.gov/pubmed/17913828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01521-07
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