Identification of Amino Acid Residues in BK Virus VP1 That Are Critical for Viability and Growth

BK virus (BKV) is a ubiquitous pathogen that establishes a persistent infection in the urinary tract of 80% of the human population. Like other polyomaviruses, the major capsid protein of BKV, virion protein 1 (VP1), is critical for host cell receptor recognition and for proper virion assembly. BKV...

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Main Authors: Dugan, Aisling S., Gasparovic, Megan L., Tsomaia, Natia, Mierke, Dale F., O'Hara, Bethany A., Manley, Kate, Atwood, Walter J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2007
Teme:
Structure and Assembly
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168807/
https://ncbi.nlm.nih.gov/pubmed/17699578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01316-07
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