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Fas Ligand Interactions Contribute to CD8(+) T-Cell-Mediated Control of West Nile Virus Infection in the Central Nervous System

West Nile virus (WNV) is a neurotropic flavivirus that causes encephalitis, most frequently in elderly and immunocompromised humans. Previous studies demonstrated that CD8(+) T cells utilize perforin-dependent cytolytic mechanisms to limit WNV infection. Nonetheless, the phenotype of perforin-defici...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shrestha, Bimmi, Diamond, Michael S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168805/
https://ncbi.nlm.nih.gov/pubmed/17804505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01136-07
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