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Estimating the Effectiveness of Simian Immunodeficiency Virus-Specific CD8(+) T Cells from the Dynamics of Viral Immune Escape

Antiviral CD8(+) T cells are thought to play a significant role in limiting the viremia of human and simian immunodeficiency virus (HIV and SIV, respectively) infections. However, it has not been possible to measure the in vivo effectiveness of cytotoxic T cells (CTLs), and hence their contribution...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mandl, Judith N., Regoes, Roland R., Garber, David A., Feinberg, Mark B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168796/
https://ncbi.nlm.nih.gov/pubmed/17699572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00946-07
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