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Disease Duration Determines Canine Distemper Virus Neurovirulence

The Morbillivirus hemagglutinin (H) protein mediates attachment to the target cell. To evaluate its contribution to canine distemper virus neurovirulence, we exchanged the H proteins of the wild-type strains 5804P and A75 and assessed the pathogenesis of the chimeric viruses in ferrets. Both strains...

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Autores principales: Bonami, François, Rudd, Penny A., von Messling, Veronika
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168775/
https://ncbi.nlm.nih.gov/pubmed/17699577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00818-07
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