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Canine Distemper Virus Epithelial Cell Infection Is Required for Clinical Disease but Not for Immunosuppression

To characterize the importance of infection of epithelial cells for morbillivirus pathogenesis, we took advantage of the severe disease caused by canine distemper virus (CDV) in ferrets. To obtain a CDV that was unable to enter epithelial cells but retained the ability to enter immune cells, we tran...

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Autores principales: Sawatsky, Bevan, Wong, Xiao-Xiang, Hinkelmann, Sarah, Cattaneo, Roberto, von Messling, Veronika
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302517/
https://ncbi.nlm.nih.gov/pubmed/22278252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06414-11
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