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Canine Distemper Virus Epithelial Cell Infection Is Required for Clinical Disease but Not for Immunosuppression

To characterize the importance of infection of epithelial cells for morbillivirus pathogenesis, we took advantage of the severe disease caused by canine distemper virus (CDV) in ferrets. To obtain a CDV that was unable to enter epithelial cells but retained the ability to enter immune cells, we tran...

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Detalhes bibliográficos
Main Authors: Sawatsky, Bevan, Wong, Xiao-Xiang, Hinkelmann, Sarah, Cattaneo, Roberto, von Messling, Veronika
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302517/
https://ncbi.nlm.nih.gov/pubmed/22278252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06414-11
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