Early Antibodies Specific for the Neutralizing Epitope on the Receptor Binding Subunit of the Lymphocytic Choriomeningitis Virus Glycoprotein Fail To Neutralize the Virus

Lymphocytic choriomeningitis virus (LCMV) is a murine arenavirus whose glycoprotein consists of a transmembrane subunit (GP-2) and a receptor-binding subunit (GP-1). LCMV-neutralizing antibodies (nAbs) are directed against a single site on GP-1 and occur 1 month after the infection of cytotoxic-T-ly...

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Bibliographic Details
Main Authors: Eschli, Bruno, Zellweger, Raphaël M., Wepf, Alexander, Lang, Karl S., Quirin, Katharina, Weber, Jacqueline, Zinkernagel, Rolf M., Hengartner, Hans
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2007
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168768/
https://ncbi.nlm.nih.gov/pubmed/17699567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00955-07
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