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Nonneutralizing antibodies binding to the surface glycoprotein of lymphocytic choriomeningitis virus reduce early virus spread

The biological relevance of nonneutralizing antibodies elicited early after infection with noncytopathic persistence-prone viruses is unclear. We demonstrate that cytotoxic T lymphocyte–deficient TgH(KL25) mice, which are transgenic for the heavy chain of the lymphocytic choriomeningitis virus (LCMV...

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Detalhes bibliográficos
Main Authors: Hangartner, Lars, Zellweger, Raphaël M., Giobbi, Mattia, Weber, Jacqueline, Eschli, Bruno, McCoy, Kathy D., Harris, Nicola, Recher, Mike, Zinkernagel, Rolf M., Hengartner, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118372/
https://ncbi.nlm.nih.gov/pubmed/16880253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051557
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