Phosphate-Controlled Regulator for the Biosynthesis of the Dalbavancin Precursor A40926

The actinomycete Nonomuraea sp. strain ATCC 39727 produces the glycopeptide A40926, the precursor of the novel antibiotic dalbavancin. Previous studies have shown that phosphate limitation results in enhanced A40926 production. The A40926 biosynthetic gene (dbv) cluster, which consists of 37 genes,...

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Autors principals: Alduina, Rosa, Piccolo, Luca Lo, D'Alia, Davide, Ferraro, Clelia, Gunnarsson, Nina, Donadio, Stefano, Puglia, Anna Maria
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2007
Matèries:
Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168674/
https://ncbi.nlm.nih.gov/pubmed/17873036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01247-07
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