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Evidence for a Common Role for the Serine-Type Plasmodium falciparum Serine Repeat Antigen Proteases: Implications for Vaccine and Drug Design

Serine repeat antigens (SERAs) are a family of secreted “cysteine-like” proteases of Plasmodium parasites. Several SERAs possess an atypical active-site serine residue in place of the canonical cysteine. The human malaria parasite Plasmodium falciparum possesses six “serine-type” (SERA1 to SERA5 and...

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Detalhes bibliográficos
Main Authors: McCoubrie, Joanne E., Miller, Susanne K., Sargeant, Tobias, Good, Robert T., Hodder, Anthony N., Speed, Terence P., de Koning-Ward, Tania F., Crabb, Brendan S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168336/
https://ncbi.nlm.nih.gov/pubmed/17893128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00405-07
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