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A New Rodent Model to Assess Blood Stage Immunity to the Plasmodium falciparum Antigen Merozoite Surface Protein 1(19) Reveals a Protective Role for Invasion Inhibitory Antibodies

Antibodies capable of inhibiting the invasion of Plasmodium merozoites into erythrocytes are present in individuals that are clinically immune to the malaria parasite. Those targeting the 19-kD COOH-terminal domain of the major merozoite surface protein (MSP)-1(19) are a major component of this inhi...

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Detalhes bibliográficos
Main Authors: de Koning-Ward, Tania F., O'Donnell, Rebecca A., Drew, Damien R., Thomson, Russell, Speed, Terence P., Crabb, Brendan S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194199/
https://ncbi.nlm.nih.gov/pubmed/12963693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030085
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