An Anti-β-Glucan Monoclonal Antibody Inhibits Growth and Capsule Formation of Cryptococcus neoformans In Vitro and Exerts Therapeutic, Anticryptococcal Activity In Vivo

In this study we tested the in vitro and in vivo anti-Cryptococcus neoformans activity of an antilaminarin (anti-β-glucan) monoclonal antibody (MAb 2G8) (immunoglobulin G2b) which was previously shown to inhibit the growth of β-glucan-exposing Candida albicans cells. Here we show that MAb 2G8 binds...

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Hlavní autoři: Rachini, Anna, Pietrella, Donatella, Lupo, Patrizia, Torosantucci, Antonella, Chiani, Paola, Bromuro, Carla, Proietti, Carla, Bistoni, Francesco, Cassone, Antonio, Vecchiarelli, Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2007
Témata:
Fungal and Parasitic Infections
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168274/
https://ncbi.nlm.nih.gov/pubmed/17606600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00278-07
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