Monoclonal Antibody to Fungal Glucosylceramide Protects Mice against Lethal Cryptococcus neoformans Infection

Glucosylceramides (GlcCer) are involved in the regulation of Cryptococcus neoformans virulence. In the present study, we demonstrate that passive immunization with a monoclonal antibody to GlcCer significantly reduces host inflammation and prolongs the survival of mice lethally infected with C. neof...

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Bibliografiske detaljer
Main Authors: Rodrigues, Marcio L., Shi, Li, Barreto-Bergter, Eliana, Nimrichter, Leonardo, Farias, Sandra E., Rodrigues, Elaine G., Travassos, Luiz R., Nosanchuk, Joshua D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2007
Fag:
Microbial Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168121/
https://ncbi.nlm.nih.gov/pubmed/17715331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00202-07
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