Monoclonal Antibody to Fungal Glucosylceramide Protects Mice against Lethal Cryptococcus neoformans Infection

Glucosylceramides (GlcCer) are involved in the regulation of Cryptococcus neoformans virulence. In the present study, we demonstrate that passive immunization with a monoclonal antibody to GlcCer significantly reduces host inflammation and prolongs the survival of mice lethally infected with C. neof...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rodrigues, Marcio L., Shi, Li, Barreto-Bergter, Eliana, Nimrichter, Leonardo, Farias, Sandra E., Rodrigues, Elaine G., Travassos, Luiz R., Nosanchuk, Joshua D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2007
Pynciau:
Microbial Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168121/
https://ncbi.nlm.nih.gov/pubmed/17715331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00202-07
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