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Ribosome Protection Prevents Azithromycin-Mediated Quorum-Sensing Modulation and Stationary-Phase Killing of Pseudomonas aeruginosa

In Pseudomonas aeruginosa, azithromycin has been shown to reduce virulence factor production, to retard biofilm formation, and to exhibit bactericidal effects on stationary-phase cells. In this study we analyzed whether these azithromycin-mediated effects require interaction with the ribosome. We bl...

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Autori principali: Köhler, Thilo, Dumas, Jean-Luc, Van Delden, Christian
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2167979/
https://ncbi.nlm.nih.gov/pubmed/17876004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00613-07
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