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Aggravated decrease in the activity of nucleus basalis neurons in Alzheimer’s disease is apolipoprotein E-type dependent
As reported before, the metabolic activity of nucleus basalis neurons is reduced significantly in Alzheimer patients. Because the apolipoprotein E (ApoE) ɛ4 genotype is a major risk factor for Alzheimer’s disease (AD), we determined whether the decrease in metabolic activity in nucleus basalis neuro...
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Main Authors: | , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
The National Academy of Sciences
1998
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC21662/ https://ncbi.nlm.nih.gov/pubmed/9736756 |
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