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Genetic code origins: tRNAs older than their synthetases?

We present a phylogenetic analysis to determine whether a given tRNA molecule was established in evolution before its cognate aminoacyl-tRNA synthetase. The earlier appearance of tRNA versus their metabolically related enzymes is a prediction of the RNA world theory, but the available synthetase and...

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Detalhes bibliográficos
Main Authors: de Pouplana, Lluís Ribas, Turner, Robert J., Steer, Brian A., Schimmel, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21636/
https://ncbi.nlm.nih.gov/pubmed/9736730
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