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Escherichia coli strains containing mutations in the structural gene for topoisomerase I are recombination deficient.

Mutations in the gene encoding topoisomerase I of Escherichia coli were tested for their effect on plasmid recombination. Recombination was decreased 1,000-fold at 30 and 37 degrees C and occurred at approximately wild-type frequencies at 42 degrees C. The suppression of topA mutations at 42 degrees...

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Détails bibliographiques
Auteurs principaux: Fishel, R A, Kolodner, R
Format: Artigo
Langue:Inglês
Publié: 1984
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC215837/
https://ncbi.nlm.nih.gov/pubmed/6094504
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