Alteration of Streptococcus pneumoniae membrane properties by the folate analog methotrexate.
The antifolate compound methotrexate (MTX) is toxic to the gram-positive bacterium Streptococcus pneumoniae. Interaction of MTX with this bacterium resulted in an increase in the electric transmembrane potential (delta psi) and enhanced the delta psi-dependent uptake of isoleucine and MTX. In contra...
Guardat en:
| Publicat a: | J Bacteriol |
|---|---|
| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1984
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC215786/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6501231/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.160.3.849-853.1984 |
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