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Alteration of Streptococcus pneumoniae membrane properties by the folate analog methotrexate.

The antifolate compound methotrexate (MTX) is toxic to the gram-positive bacterium Streptococcus pneumoniae. Interaction of MTX with this bacterium resulted in an increase in the electric transmembrane potential (delta psi) and enhanced the delta psi-dependent uptake of isoleucine and MTX. In contra...

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Detaylı Bibliyografya
Yayımlandı:J Bacteriol
Yazar: Trombe, M C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1984
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC215786/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6501231/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.160.3.849-853.1984
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