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Interaction of Spin-Labeled Inhibitors of the Vacuolar H(+)-ATPase with the Transmembrane V(o)-Sector
The osteoclast variant of the vacuolar H(+)-ATPase (V-ATPase) is a potential therapeutic target for combating the excessive bone resorption that is involved in osteoporosis. The most potent in a series of synthetic inhibitors based on 5-(5,6-dichloro-2-indolyl)-2-methoxy-2,4-pentadienamide (INDOL0)...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Biophysical Society
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2157245/ https://ncbi.nlm.nih.gov/pubmed/17872954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.111781 |
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