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Monitoring Receptor-Ligand Interactions between Surfaces by Thermal Fluctuations

We describe a new method for determining receptor-ligand association/dissociation events across the interface of two surfaces (two-dimensional binding) by monitoring abrupt decrease/resumption in thermal fluctuations of a biomembrane force probe. Our method has been validated by rigorous control exp...

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Bibliographic Details
Main Authors: Chen, Wei, Evans, Evan A., McEver, Rodger P., Zhu, Cheng
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2157231/
https://ncbi.nlm.nih.gov/pubmed/17890399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.117895
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