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The antisense bcl-2–IgH transcript is an optimal target for synthetic oligonucleotides
In most human follicular B cell lymphomas the bcl-2 gene is up-regulated as a result of the t(14;18) chromosomal translocation generating a hybrid bcl-2–IgH mRNA. Recently, we have identified in t(14;18)-positive cells a bcl-2–IgH mRNA in the antisense orientation, putatively responsible for the ove...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The National Academy of Sciences of the USA
1997
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC21572/ https://ncbi.nlm.nih.gov/pubmed/9223330 |
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