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The Spinal Muscular Atrophy Disease Gene Product, Smn: A Link between Snrnp Biogenesis and the Cajal (Coiled) Body

The spliceosomal snRNAs U1, U2, U4, and U5 are synthesized in the nucleus, exported to the cytoplasm to assemble with Sm proteins, and reimported to the nucleus as ribonucleoprotein particles. Recently, two novel proteins involved in biogenesis of small nuclear ribonucleoproteins (snRNPs) were ident...

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Bibliographic Details
Main Authors: Carvalho, Teresa, Almeida, Fátima, Calapez, Alexandre, Lafarga, Miguel, Berciano, Maria T., Carmo-Fonseca, Maria
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2156166/
https://ncbi.nlm.nih.gov/pubmed/10562276
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