Mcm2, but Not Rpa, Is a Component of the Mammalian Early G1-Phase Prereplication Complex

Previous experiments in Xenopus egg extracts identified what appeared to be two independently assembled prereplication complexes (pre-RCs) for DNA replication: the stepwise assembly of ORC, Cdc6, and Mcm onto chromatin, and the FFA-1–mediated recruitment of RPA into foci on chromatin. We have invest...

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Bibliographic Details
Main Authors: Dimitrova, Daniela S., Todorov, Ivan T., Melendy, Thomas, Gilbert, David M.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1999
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2156148/
https://ncbi.nlm.nih.gov/pubmed/10459007
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