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Convergent Use of RhoGAP Toxins by Eukaryotic Parasites and Bacterial Pathogens

Inactivation of host Rho GTPases is a widespread strategy employed by bacterial pathogens to manipulate mammalian cellular functions and avoid immune defenses. Some bacterial toxins mimic eukaryotic Rho GTPase-activating proteins (GAPs) to inactivate mammalian GTPases, probably as a result of evolut...

詳細記述

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書誌詳細
主要な著者: Colinet, Dominique, Schmitz, Antonin, Depoix, Delphine, Crochard, Didier, Poirié, Marylène
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2156102/
https://ncbi.nlm.nih.gov/pubmed/18166080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030203
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