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Convergent Use of RhoGAP Toxins by Eukaryotic Parasites and Bacterial Pathogens

Inactivation of host Rho GTPases is a widespread strategy employed by bacterial pathogens to manipulate mammalian cellular functions and avoid immune defenses. Some bacterial toxins mimic eukaryotic Rho GTPase-activating proteins (GAPs) to inactivate mammalian GTPases, probably as a result of evolut...

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Detalhes bibliográficos
Main Authors: Colinet, Dominique, Schmitz, Antonin, Depoix, Delphine, Crochard, Didier, Poirié, Marylène
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2156102/
https://ncbi.nlm.nih.gov/pubmed/18166080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030203
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