Gap junction remodeling and cardiac arrhythmogenesis in a murine model of oculodentodigital dysplasia

Gap junction channels are required for normal cardiac impulse propagation, and gap junction remodeling is associated with enhanced arrhythmic risk. Oculodentodigital dysplasia (ODDD) is a multisystem syndrome due to mutations in the connexin43 (Cx43) gap junction channel gene. To determine the effec...

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Detalhes bibliográficos
Main Authors: Kalcheva, Nellie, Qu, Jiaxiang, Sandeep, Nefthi, Garcia, Luis, Zhang, Jie, Wang, Zhiyong, Lampe, Paul D., Suadicani, Sylvia O., Spray, David C., Fishman, Glenn I.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154462/
https://ncbi.nlm.nih.gov/pubmed/18077386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705472105
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